KEAP1 antibody
Product Specifications
Background
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
Synonyms
Kelch-like ECH-associated protein 1|Cytosolic inhibitor of Nrf2 (INrf2) |Kelch-like protein 19|KEAP1|INRF2|KIAA0132|KLHL19
Gene ID
9817
UniProt
Q14145
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Kelch-like ECH-associated protein 1
Target
KEAP1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, IF, WB
Field of Research
Cancer, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
55-80 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, IF, WB
Immunogen Sequence
378-486aa
Curated Selection
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