KCNE1 antibody
Product Specifications
Background
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 (PubMed:19219384) . Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr) .
Synonyms
Potassium voltage-gated channel subfamily E member 1|Delayed rectifier potassium channel subunit IsK|IKs producing slow voltage-gated potassium channel subunit beta Mink|Minimal potassium channel|KCNE1
Gene ID
3753
UniProt
P15382
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Potassium voltage-gated channel, Isk-related family, member 1
Target
KCNE1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Neuroscience, Cardiovascular
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
18-25 kDa, 28-35 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF
Curated Selection
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