ITPKB antibody
Product Specifications
Background
The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1, 4, 5-trisphosphate to Ins (1, 3, 4, 5) P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.
Synonyms
Inositol-trisphosphate 3-kinase B|Inositol 1,4,5-trisphosphate 3-kinase B (IP3 3-kinase B, IP3K B, InsP 3-kinase B) |ITPKB
Gene ID
3707
UniProt
P27987
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Inositol 1, 4, 5-trisphosphate 3-kinase B
Target
ITPKB
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:200 - 1:2000; IHC: 1:20 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
102 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
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