ITPKB antibody

Product Specifications

Background

The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1, 4, 5-trisphosphate to Ins (1, 3, 4, 5) P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.

Synonyms

Inositol-trisphosphate 3-kinase B|Inositol 1,4,5-trisphosphate 3-kinase B (IP3 3-kinase B, IP3K B, InsP 3-kinase B) |ITPKB

Gene ID

3707

UniProt

P27987

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Inositol 1, 4, 5-trisphosphate 3-kinase B

Target

ITPKB

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Signal Transduction

Purification

Immunogen affinity purified

Dilution

WB: 1:200 - 1:2000; IHC: 1:20 - 1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

102 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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