ITPA antibody
Product Specifications
Background
Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy-and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
Synonyms
Inosine triphosphate pyrophosphatase (ITPase, Inosine triphosphatase) |Non-canonical purine NTP pyrophosphatase|Non-standard purine NTP pyrophosphatase|Nucleoside-triphosphate diphosphatase|Nucleoside-triphosphate pyrophosphatase (NTPase) |Putative oncogene protein hlc14-06-p|ITPA|C20orf37
Gene ID
3704
UniProt
Q9BY32
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
Target
ITPA
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, IHC, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
22 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF, IHC, IP
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