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ISG15 antibody

Product Specifications

Background

The protein encoded by this gene is a ubiquitin-like protein that is conjugated to intracellular target proteins upon activation by interferon-alpha and interferon-beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted.

Synonyms

Ubiquitin-like protein ISG15|Interferon-induced 15 kDa protein|Interferon-induced 17 kDa protein (IP17) |Ubiquitin cross-reactive protein (hUCRP) |ISG15|G1P2|UCRP

Gene ID

9636

UniProt

P05161

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

ISG15 ubiquitin-like modifier

Target

ISG15

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Epigenetics, Immunology, Signal Transduction, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:2000; IHC: :1:50 - 1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

14 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

Immunogen Sequence

2-157aa

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