IREB2 antibody
Product Specifications
Background
RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
Synonyms
Iron-responsive element-binding protein 2 (IRE-BP 2) |Iron regulatory protein 2 (IRP2) |IREB2
Gene ID
3658
UniProt
P48200
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Iron-responsive element binding protein 2
Target
IREB2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Cardiovascular, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
90-105 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF
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