ITGB1 antibody
Product Specifications
Background
Integrin beta-1 (ITGB1), also named as CD29, is a 130 kDa single chain type I glycoprotein that is expressed in a heterodimeric complex with one of six distinct α subunits, comprising the very late activation antigen (VLA) subfamily of adhesion receptors. It is one of the essential surface molecules expressed on human MSC from bone marrow and other sources. The β1 subunit is also broadly expressed on lymphocytes and monocytes, weakly expressed on granulocytes, and not expressed on erythrocytes. These receptors are involved in a variety of cell-cell and cell-matrix interactions.
Synonyms
Integrin beta-1|Fibronectin receptor subunit beta|Glycoprotein IIa (GPIIA) |VLA-4 subunit beta|ITGB1|FNRB|MDF2|MSK12
Gene ID
3688
UniProt
P05556
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Integrin, beta 1
Target
ITGB1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB,IHC
Field of Research
Signal Transduction, Cardiovascular, Immunology, Cancer, Neuroscience, Stem Cells
Purification
Immunogen affinity purified
Dilution
WB: 1:1000-1:4000; IHC: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
130 kDa, 100 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
76-206aa
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