ITGA4 antibody
Product Specifications
Background
ITGA4, also named as CD49D, belongs to the integrin alpha chain family. ITGA4 is a receptor for fibronectin, VCAM1 and MADCAM1. ITGA4 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. It recognizes the sequence Q-I-D-S in VCAM1. I It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells ITGA4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.
Synonyms
Integrin alpha-4|CD49 antigen-like family member D|Integrin alpha-IV|VLA-4 subunit alpha|ITGA4|CD49D
Gene ID
3676
UniProt
P13612
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Integrin, alpha 4
Target
ITGA4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Stem Cells, Immunology, Cardiovascular
Purification
Immunogen affinity purified
Dilution
WB: 1500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
140 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
231-444
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