IMPDH2 antibody
Product Specifications
Background
Catalyzes the conversion of inosine 5'-phosphate(IMP) to xanthosine 5'-phosphate(XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
Synonyms
Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2, IMPD 2, IMPDH 2)|Inosine-5'-monophosphate dehydrogenase type II (IMP dehydrogenase II, IMPDH-II)|IMPDH2|IMPD2
Gene ID
3615
UniProt
P12268
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
IMP(inosine monophosphate) dehydrogenase 2
Target
IMPDH2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
56 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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