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IMPDH1 antibody

Product Specifications

Background

Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.

Synonyms

Inosine-5'-monophosphate dehydrogenase 1 (IMP dehydrogenase 1, IMPD 1, IMPDH 1) |IMPDH-I|IMPDH1|IMPD1

Gene ID

3614

UniProt

P20839

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

IMP (inosine monophosphate) dehydrogenase 1

Target

IMPDH1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Neuroscience, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

53-60 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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