IMPDH1 antibody
Product Specifications
Background
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
Synonyms
Inosine-5'-monophosphate dehydrogenase 1 (IMP dehydrogenase 1, IMPD 1, IMPDH 1) |IMPDH-I|IMPDH1|IMPD1
Gene ID
3614
UniProt
P20839
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
IMP (inosine monophosphate) dehydrogenase 1
Target
IMPDH1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
53-60 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
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