IL6R antibody
Product Specifications
Background
Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis. Low concentration of a soluble form of IL6 receptor acts as an agonist of IL6 activity.
Synonyms
Interleukin-6 receptor subunit alpha (IL-6 receptor subunit alpha, IL-6R subunit alpha, IL-6R-alpha, IL-6RA) |IL-6R 1|Membrane glycoprotein 80 (gp80) |Soluble interleukin-6 receptor subunit alpha (sIL6R) |IL6R
Gene ID
3570
UniProt
P08887
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Interleukin 6 receptor
Target
IL6R
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Stem Cells, Immunology, Cardiovascular, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IHC: 1:50-1:200; IP: 1:500-1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
80 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP
Immunogen Sequence
P08887-1,229-468
Curated Selection
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