IL37 antibody
Product Specifications
Background
Suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. This function requires SMAD3. Suppresses, or reduces, proinflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spares anti-inflammatory cytokines. Inhibits dendritic cell activation.
Synonyms
Interleukin-37 (IL-37) |FIL1 zeta|IL-1X|Interleukin-1 family member 7 (IL-1F7) |Interleukin-1 homolog 4 (IL-1H, IL-1H4) |Interleukin-1 zeta (IL-1 zeta) |Interleukin-1-related protein (IL-1RP1) |IL37|FIL1Z|IL1F7|IL1H4|IL1RP1
Gene ID
27178
UniProt
Q9NZH6
Host
Rabbit
Reactivity
Human
Immunogen
Interleukin 1 family, member 7 (zeta)
Target
IL37
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Immunology, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:1000-1:4000; IHC: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
24 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
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