IL33 antibody
Product Specifications
Background
Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells(PubMed:16286016). Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury(PubMed:17853410, PubMed:18836528).
Synonyms
Interleukin-33 (IL-33)|Interleukin-1 family member 11 (IL-1F11)|Nuclear factor from high endothelial venules (NF-HEV)|Interleukin-33 (95-270)|Interleukin-33 (99-270)|Interleukin-33 (109-270)|IL33|C9orf26|IL1F11|NFHEV
Gene ID
90865
UniProt
O95760
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
interleukin 33
Target
IL33
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB
Field of Research
Immunology, Cardiovascular
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
35 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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