IL22RA1 antibody
Product Specifications
Background
Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.
Synonyms
Interleukin-22 receptor subunit alpha-1 (IL-22 receptor subunit alpha-1, IL-22R-alpha-1, IL-22RA1) |Cytokine receptor class-II member 9|Cytokine receptor family 2 member 9 (CRF2-9) |ZcytoR11|IL22RA1|IL22R
Gene ID
58985
UniProt
Q8N6P7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Interleukin 22 receptor, alpha 1
Target
IL22RA1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Immunology, Cardiovascular, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
62 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF
Immunogen Sequence
16-228aa
Curated Selection
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