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IL21 antibody

Product Specifications

Background

This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Synonyms

Interleukin-21 (IL-21)|Za11|IL21

Gene ID

59067

UniProt

Q9HBE4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

interleukin 21

Target

IL21

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Immunology, Signal Transduction, Developmental biology

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

18 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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