IL12RB1 antibody
Product Specifications
Background
Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.
Synonyms
Interleukin-12 receptor subunit beta-1 (IL-12 receptor subunit beta-1, IL-12R subunit beta-1, IL-12R-beta-1, IL-12RB1) |IL-12 receptor beta component|IL12RB1|IL12R|IL12RB
Gene ID
3594
UniProt
P42701
Host
Rabbit
Reactivity
Human
Immunogen
Interleukin 12 receptor, beta 1
Target
IL12RB1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Immunology, Cardiovascular, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
100 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
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