IL11RA antibody
Product Specifications
Background
Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.
Synonyms
Interleukin-11 receptor subunit alpha (IL-11 receptor subunit alpha, IL-11R subunit alpha, IL-11R-alpha, IL-11RA) |Soluble interleukin-11 receptor subunit alpha (sIL-11R, sIL-11RA, sIL11RA) |IL11RA
Gene ID
3590
UniProt
Q14626
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Interleukin 11 receptor, alpha
Target
IL11RA
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, FC
Field of Research
Immunology, Cardiovascular, Developmental biology, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:1000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
45 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF, FC
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