NFKBIA antibody
Product Specifications
Background
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
Synonyms
NF-kappa-B inhibitor alpha|I-kappa-B-alpha (IkB-alpha, IkappaBalpha) |Major histocompatibility complex enhancer-binding protein MAD3|NFKBIA|IKBA|MAD3|NFKBI
Gene ID
4792
UniProt
P25963
Host
Rabbit
Reactivity
Human, Mouse, Rat, Pig
Immunogen
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
Target
NFKBIA
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, IF, WB, IP, FC
Field of Research
Epigenetics, Signal Transduction, Metabolism, Cardiovascular, Immunology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
39 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, IF, WB, IP, FC
Curated Selection
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