IGF2BP3 antibody
Product Specifications
Background
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.
Synonyms
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3, IMP-3) |IGF-II mRNA-binding protein 3|KH domain-containing protein overexpressed in cancer (hKOC) |VICKZ family member 3|IGF2BP3|IMP3|KOC1|VICKZ3
Gene ID
10643
UniProt
O00425
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Insulin-like growth factor 2 mRNA binding protein 3
Target
IGF2BP3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Epigenetics, Cancer, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
72 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
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