IFNGR2 antibody
Product Specifications
Background
Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:8124716, PubMed:7673114, PubMed:7615558) . Ligand binding stimulates activation of the JAK/STAT signaling pathway (PubMed:8124716, PubMed:7673114, PubMed:15356148) . Required for signal transduction in contrast to other receptor subunit responsible for ligand binding (PubMed:7673114) .
Synonyms
Interferon gamma receptor 2 (IFN-gamma receptor 2, IFN-gamma-R2) |Interferon gamma receptor accessory factor 1 (AF-1) |Interferon gamma receptor beta-chain (IFN-gamma-R-beta) |Interferon gamma transducer 1|IFNGR2|IFNGT1
Gene ID
3460
UniProt
P38484
Host
Rabbit
Reactivity
Human
Immunogen
Interferon gamma receptor 2 (interferon gamma transducer 1)
Target
IFNGR2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Neuroscience, Immunology, Cardiovascular, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50-55 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
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