IFNAR1 antibody
Product Specifications
Background
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.
Synonyms
Interferon alpha/beta receptor 1 (IFN-R-1, IFN-alpha/beta receptor 1) |Cytokine receptor class-II member 1|Cytokine receptor family 2 member 1 (CRF2-1) |Type I interferon receptor 1|IFNAR1|IFNAR
Gene ID
3454
UniProt
P17181
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Interferon (alpha, beta and omega) receptor 1
Target
IFNAR1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB
Field of Research
Immunology, Cardiovascular, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
70 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB
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