MitoEbselen-2 (chloride)
MitoEbselen-2 chloride (MitoPeroxidase 2), a mitochondria-targeted mimic of glutathione peroxidase, is a radiation mitigator. MitoEbselen-2 chloride is effective in reducing lipid hydroperoxides, preventing apoptotic cell death[1].
Product Specifications
CAS Number
[1638973-78-0]
Product Name Alternative
MitoPeroxidase 2
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/mitoebselen-2-chloride.html
Purity
97.0
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(NCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)CC4=CC=C(N5[Se]C6=C(C=CC=C6)C5=O)C=C4.[Cl-]
Molecular Formula
C35H30ClN2O2PSe
Molecular Weight
656.01
References & Citations
[1]Stoyanovsky DA, et, al. Design and Synthesis of a Mitochondria-Targeted Mimic of Glutathione Peroxidase, MitoEbselen-2, as a Radiation Mitigator. ACS Med Chem Lett. 2014 Nov 18;5 (12) :1304-1307.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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