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HTR3A antibody

Product Specifications

Background

The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.

Synonyms

5-hydroxytryptamine receptor 3A (5-HT3-A, 5-HT3A)|5-hydroxytryptamine receptor 3 (5-HT-3, 5-HT3R)|Serotonin receptor 3A|Serotonin-gated ion channel receptor|HTR3A|5HT3R|HTR3

Gene ID

3359

UniProt

P46098

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

5-hydroxytryptamine (serotonin) receptor 3A

Target

HTR3A

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Neuroscience, Signal Transduction, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

55 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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