HTR3A antibody
Product Specifications
Background
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms
5-hydroxytryptamine receptor 3A (5-HT3-A, 5-HT3A)|5-hydroxytryptamine receptor 3 (5-HT-3, 5-HT3R)|Serotonin receptor 3A|Serotonin-gated ion channel receptor|HTR3A|5HT3R|HTR3
Gene ID
3359
UniProt
P46098
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
5-hydroxytryptamine (serotonin) receptor 3A
Target
HTR3A
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience, Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
55 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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