HSPBP1 antibody
Product Specifications
Background
Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.
Synonyms
Hsp70-binding protein 1 (HspBP1) |Heat shock protein-binding protein 1|Hsp70-binding protein 2 (HspBP2) |Hsp70-interacting protein 1|Hsp70-interacting protein 2|HSPBP1|HSPBP
Gene ID
23640
UniProt
Q9NZL4
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
Target
HSPBP1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
40 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
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