HSPA1L antibody
Product Specifications
Background
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage(By similarity). Positive regulator of PARK2 translocation to damaged mitochondria.
Synonyms
Heat shock 70 kDa protein 1-like (Heat shock 70 kDa protein 1L)|Heat shock 70 kDa protein 1-Hom (HSP70-Hom)|HSPA1L
Gene ID
3305
UniProt
P34931
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
heat shock 70kDa protein 1-like
Target
HSPA1L
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, IF, WB
Field of Research
Immunology, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
70 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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