HSD17B8 antibody
Product Specifications
Background
NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heterotetramer with CBR4 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria.
Synonyms
(3R)-3-hydroxyacyl-CoA dehydrogenase|17-beta-hydroxysteroid dehydrogenase 8 (17-beta-HSD 8, HSD17B8)|3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit (KAR alpha subunit)|3-oxoacyl-[acyl-carrier-protein] reductase|Estradiol 17-beta-dehydrogenase 8|Protein Ke6 (Ke6)|Short chain dehydrogenase/reductase family 30C member 1|Testosterone 17-beta-dehydrogenase 8|HSD17B8|FABGL|HKE6|RING2|SDR30C1
Gene ID
7923
UniProt
Q92506
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
hydroxysteroid(17-beta) dehydrogenase 8
Target
HSD17B8
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
34 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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