HSD17B11 antibody
Product Specifications
Background
Can convert androstan-3-alpha,17-beta-diol(3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA(dehydroepiandrosterone), or A-dione(4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma.
Synonyms
Estradiol 17-beta-dehydrogenase 11|17-beta-hydroxysteroid dehydrogenase 11 (17-beta-HSD 11, 17bHSD11, 17betaHSD11)|17-beta-hydroxysteroid dehydrogenase XI (17-beta-HSD XI, 17betaHSDXI)|Cutaneous T-cell lymphoma-associated antigen HD-CL-03 (CTCL-associated antigen HD-CL-03)|Dehydrogenase/reductase SDR family member 8|Retinal short-chain dehydrogenase/reductase 2 (retSDR2)|Short chain dehydrogenase/reductase family 16C member 2|HSD17B11|DHRS8|PAN1B|SDR16C2
Gene ID
51170
UniProt
Q8NBQ5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
hydroxysteroid(17-beta) dehydrogenase 11
Target
HSD17B11
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
33 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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