HSD11B2 antibody
Product Specifications
Background
Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
Synonyms
11-beta-hydroxysteroid dehydrogenase type 2 (11-DH2, 11-beta-HSD2) |11-beta-hydroxysteroid dehydrogenase type II (11-HSD type II, 11-beta-HSD type II) |Corticosteroid 11-beta-dehydrogenase isozyme 2|NAD-dependent 11-beta-hydroxysteroid dehydrogenase|Short chain dehydrogenase/reductase family 9C member 3|HSD11B2|HSD11K|SDR9C3
Gene ID
3291
UniProt
P80365
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Hydroxysteroid (11-beta) dehydrogenase 2
Target
HSD11B2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
40-43 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
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