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HS3ST1 antibody

Product Specifications

Background

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate(PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan. Catalyzes the rate limiting step in the biosynthesis of heparan sulfate(HSact). This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site.

CAS Number

9007-83-4

Synonyms

Heparan sulfate glucosamine 3-O-sulfotransferase 1|Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1 (3-OST-1, Heparan sulfate 3-O-sulfotransferase 1, h3-OST-1)|HS3ST1|3OST|3OST1

Gene ID

9957

UniProt

O14792

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

heparan sulfate(glucosamine) 3-O-sulfotransferase 1

Target

HS3ST1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Cardiovascular, Metabolism, Developmental biology, Signal Transduction

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

46 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

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