HPS4 antibody
Product Specifications
Background
Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38 (PubMed:23084991) .
Synonyms
BLOC-3 complex member HPS4|Hermansky-Pudlak syndrome 4 protein|Light-ear protein homolog|HPS4|KIAA1667
Gene ID
89781
UniProt
Q9NQG7
Host
Rabbit
Reactivity
Human
Immunogen
Hermansky-Pudlak syndrome 4
Target
HPS4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, IP, IHC
Field of Research
Neuroscience
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
70 kDa and 90 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF, IP, IHC
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