HNRNPA1 antibody
Product Specifications
Background
This gene encodes a member of a family of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs), which are RNA-binding proteins that associate with pre-mRNAs in the nucleus and influence pre-mRNA processing, as well as other aspects of mRNA metabolism and transport. The protein encoded by this gene is one of the most abundant core proteins of hnRNP complexes and plays a key role in the regulation of alternative splicing. Mutations in this gene have been observed in individuals with amyotrophic lateral sclerosis 20. Multiple alternatively spliced transcript variants have been found. There are numerous pseudogenes of this gene distributed throughout the genome.
Synonyms
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1)|Helix-destabilizing protein|Single-strand RNA-binding protein|hnRNP core protein A1|Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed|HNRNPA1|HNRPA1
Gene ID
3178
UniProt
P09651
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
heterogeneous nuclear ribonucleoprotein A1
Target
HNRNPA1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Neuroscience, Metabolism, Epigenetics
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
39 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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