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HMOX1 antibody

Product Specifications

Background

Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.

Synonyms

Heme oxygenase 1 (HO-1) |Heme oxygenase 1 soluble form|HMOX1|HO|HO1

Gene ID

3162

UniProt

P09601

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Heme oxygenase (decycling) 1

Target

HMOX1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IP, IF

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:1000; IP: 1:500-1:2000; IHC: 1:100-1:400; IF: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

33 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IP, IF

Immunogen Sequence

1-267aa

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