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H2AC25 antibody

Product Specifications

Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Synonyms

Histone H2A type 3|H2A-clustered histone 25|H2AC25|H2AW|HIST3H2A

Gene ID

92815

UniProt

Q7L7L0

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Histone cluster 3, H2a

Target

H2AC25

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Epigenetics, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:1000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

16 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB

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