HDAC6 antibody
Product Specifications
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
Synonyms
Histone deacetylase 6 (HD6) |Tubulin-lysine deacetylase HDAC6|HDAC6|KIAA0901
Gene ID
10013
UniProt
Q9UBN7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Histone deacetylase 6
Target
HDAC6
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Epigenetics, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP : 1:20 - 1:50
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
170 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP
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