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HDAC2 antibody

Product Specifications

Background

This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4) . This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.

Synonyms

Histone deacetylase 2 (HD2) |Protein deacylase HDAC2|HDAC2

Gene ID

3066

UniProt

Q92769

Host

Rabbit

Reactivity

Human, Mouse, Rat, Monkey

Immunogen

Histone deacetylase 2

Target

HDAC2

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IF, IP

Field of Research

Epigenetics, Cardiovascular, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100; IP: 1:50 - 1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

56 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IF, IP

Immunogen Sequence

386-488

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