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GTF2IRD1 antibody

Product Specifications

Background

May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1) . Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8 (By similarity) .

Synonyms

General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) |General transcription factor III|MusTRD1/BEN|Muscle TFII-I repeat domain-containing protein 1|Slow-muscle-fiber enhancer-binding protein|USE B1-binding protein|Williams-Beuren syndrome chromosomal region 11 protein|Williams-Beuren syndrome chromosomal region 12 protein|GTF2IRD1|CREAM1|GTF3|MUSTRD1|RBAP2|WBSCR11|WBSCR12

Gene ID

9569

UniProt

Q9UHL9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

GTF2I repeat domain containing 1

Target

GTF2IRD1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Metabolism, Developmental biology

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

145 kDa, 120 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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