GTF2IRD1 antibody
Product Specifications
Background
May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1) . Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8 (By similarity) .
Synonyms
General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) |General transcription factor III|MusTRD1/BEN|Muscle TFII-I repeat domain-containing protein 1|Slow-muscle-fiber enhancer-binding protein|USE B1-binding protein|Williams-Beuren syndrome chromosomal region 11 protein|Williams-Beuren syndrome chromosomal region 12 protein|GTF2IRD1|CREAM1|GTF3|MUSTRD1|RBAP2|WBSCR11|WBSCR12
Gene ID
9569
UniProt
Q9UHL9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
GTF2I repeat domain containing 1
Target
GTF2IRD1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
145 kDa, 120 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
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