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GSK3B antibody

Product Specifications

Background

Glycogen synthase kinase-3(GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase.GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.In skeletal muscle, it contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Researches showed that the crystal structure of human GSK3B, expressed in insect cells, at 2.8-angstrom resolution.This antibody recognize the C-terminal of GSK3B.

Synonyms

Glycogen synthase kinase-3 beta (GSK-3 beta)|Serine/threonine-protein kinase GSK3B|GSK3B

Gene ID

2932

UniProt

P49841

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

glycogen synthase kinase 3 beta

Target

GSK3B

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IF, IP

Field of Research

Signal Transduction, Metabolism, Cardiovascular, Immunology, Developmental biology, Neuroscience, Cell Division and Proliferation

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

50 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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