HSP90B1 antibody
Product Specifications
Background
HSP90 proteins are highly conserved molecular chaperones, which normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90B1 (GP96 or GRP94) is an endoplasmic reticulum paralogue of the cytosolic HSP90. As a major ER chaperone to mediate the UPR and a master chaperone for Toll-like receptors (TLRs), HSP90b1 chaperones peptides to MHC class I molecules of dendritic cells and other antigen-presenting cells, as well as facilitating the assembly of immunoglobulin. The protein is also involved in many other bio-processes. This antibody was generated against the C-terminal region of full-length HSP90b1.
Synonyms
Endoplasmin|94 kDa glucose-regulated protein (GRP-94) |Heat shock protein 90 kDa beta member 1|Tumor rejection antigen 1|gp96 homolog|HSP90B1|GRP94|TRA1
UniProt
P14625
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Heat shock protein 90kDa beta (Grp94), member 1
Target
HSP90B1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, FC, IF, IP
Field of Research
Neuroscience, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:1000-1:4000; IP: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
94 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, FC, IF, IP
Curated Selection
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