HSPA9 antibody
Product Specifications
Background
GRP75 (also known as mortalin, HSPA9 or mt-Hsp70) is a constitutively expressed member of the HSPA (HSP70) family of heat-shock proteins. It is located in the mitochondrial matrix and anti-GRP75 is commonly used as the marker for mitochondria. It has been reported that GRP75 is enriched in cancer cells and contributes to carcinogenesis. In addition, decreased expression level of GRP75 has been found in neurodegenerative disorders like Parkinson’s disease.
Synonyms
Stress-70 protein, mitochondrial|75 kDa glucose-regulated protein (GRP-75) |Heat shock 70 kDa protein 9|Mortalin (MOT) |Peptide-binding protein 74 (PBP74) |HSPA9|GRP75|HSPA9B|mt-HSP70
UniProt
P38646
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Heat shock 70kDa protein 9 (mortalin)
Target
HSPA9
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, FC, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:1000-1:4000; IP: 1:1000-1:4000; IHC: 1:20-1:200; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
74 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF, FC, IP
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