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GPT antibody

Product Specifications

Background

This gene encodes cytosolic alanine aminotransaminase 1 (ALT1) ; also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.

Synonyms

Alanine aminotransferase 1 (ALT1) |Glutamate pyruvate transaminase 1 (GPT 1) |Glutamic--alanine transaminase 1|Glutamic--pyruvic transaminase 1|GPT|AAT1|GPT1

Gene ID

2875

UniProt

P24298

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Glutamic-pyruvate transaminase (alanine aminotransferase)

Target

GPT

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Stem Cells, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:200 - 1:1000; IHC: 1:50 - 1:100

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

50 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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