GPT antibody
Product Specifications
Background
This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.
Synonyms
Alanine aminotransferase 1 (ALT1)|Glutamate pyruvate transaminase 1 (GPT 1)|Glutamic--alanine transaminase 1|Glutamic--pyruvic transaminase 1|GPT|AAT1|GPT1
Gene ID
2875
UniProt
P24298
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
glutamic-pyruvate transaminase (alanine aminotransferase)
Target
GPT
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Stem Cells, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200 - 1:1000; IHC: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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