GOPC antibody
Product Specifications
Background
Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels. May also regulate the intracellular trafficking of the ADR1B receptor. May play a role in autophagy. Overexpression results in CFTR intracellular retention and degradation in the lysosomes.
Synonyms
Golgi-associated PDZ and coiled-coil motif-containing protein|CFTR-associated ligand|Fused in glioblastoma|PDZ protein interacting specifically with TC10 (PIST) |GOPC|CAL|FIG
Gene ID
57120
UniProt
Q9HD26
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Golgi associated PDZ and coiled-coil motif containing
Target
GOPC
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
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