GOPC antibody

Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels. May also regulate the intracellular trafficking of the ADR1B receptor. May play a role in autophagy. Overexpression results in CFTR intracellular retention and degradation in the lysosomes.

Golgi-associated PDZ and coiled-coil motif-containing protein|CFTR-associated ligand|Fused in glioblastoma|PDZ protein interacting specifically with TC10 (PIST) |GOPC|CAL|FIG