GNAI2 antibody
Product Specifications
Background
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G (i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division. Isoform sGi2: Regulates the cell surface density of dopamine receptors DRD2 by sequestrating them as an intracellular pool.
Synonyms
Guanine nucleotide-binding protein G (i) subunit alpha-2|Adenylate cyclase-inhibiting G alpha protein|GNAI2|GNAI2B
Gene ID
2771
UniProt
P04899
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
Target
GNAI2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, IHC, IP
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
35-40 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF, IHC, IP
Curated Selection
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