GLYR1 antibody
Product Specifications
Background
May have oxidoreductase activity. Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling. Indirectly promotes phosphorylation of MAPK14 and activation of ATF2. The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6. Recruited on chromatin, recognizes and binds trimethylated 'Lys-36' of histone H3(H3K36me3).
Synonyms
Cytokine-like nuclear factor N-PAC (NPAC)|3-hydroxyisobutyrate dehydrogenase-like protein|Glyoxylate reductase 1 homolog|Nuclear protein NP60|Nuclear protein of 60 kDa|Nucleosome-destabilizing factor (hNDF)|Putative oxidoreductase GLYR1|GLYR1|HIBDL|NDF|NP60|NPAC
Gene ID
84656
UniProt
Q49A26
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
cytokine-like nuclear factor n-pac
Target
GLYR1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
60 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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