GGA2 antibody
Product Specifications
Background
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly.
Synonyms
ADP-ribosylation factor-binding protein GGA2|Gamma-adaptin-related protein 2|Golgi-localized, gamma ear-containing, ARF-binding protein 2|VHS domain and ear domain of gamma-adaptin (Vear) |GGA2|KIAA1080
Gene ID
23062
UniProt
Q9UJY4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Golgi associated, gamma adaptin ear containing, ARF binding protein 2
Target
GGA2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
72 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB, IF
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