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GFRA2 antibody

Product Specifications

Background

Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. Isoform 2: Participates to NRTN-induced 'Ser-727' phosphorylation of STAT3.

Synonyms

GDNF family receptor alpha-2 (GDNF receptor alpha-2, GDNFR-alpha-2, GFR-alpha-2) |GDNF receptor beta (GDNFR-beta) |Neurturin receptor alpha (NRTNR-alpha, NTNR-alpha) |RET ligand 2|TGF-beta-related neurotrophic factor receptor 2|GFRA2|GDNFRB|RETL2|TRNR2

Gene ID

2675

UniProt

O00451

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

GDNF family receptor alpha 2

Target

GFRA2

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Neuroscience

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

34-40 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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