GFRA2 antibody
Product Specifications
Background
Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.
Isoform 2: Participates to NRTN-induced 'Ser-727' phosphorylation of STAT3.
Synonyms
GDNF family receptor alpha-2 (GDNF receptor alpha-2, GDNFR-alpha-2, GFR-alpha-2)|GDNF receptor beta (GDNFR-beta)|Neurturin receptor alpha (NRTNR-alpha, NTNR-alpha)|RET ligand 2|TGF-beta-related neurotrophic factor receptor 2|GFRA2|GDNFRB|RETL2|TRNR2
Gene ID
2675
UniProt
O00451
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
GDNF family receptor alpha 2
Target
GFRA2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
34-40 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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