GBP5 antibody
Product Specifications
Background
As an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, agents (PubMed:22461501) . Hydrolyzes GTP, but in contrast to other family members, does not produce GMP (PubMed:20180847) .
Synonyms
Guanylate-binding protein 5|GBP-TA antigen|GTP-binding protein 5 (GBP-5) |Guanine nucleotide-binding protein 5|GBP5
Gene ID
115362
UniProt
Q96PP8
Host
Rabbit
Reactivity
Human
Immunogen
Guanylate binding protein 5
Target
GBP5
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, IF, WB, FC
Field of Research
Immunology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
65 kDa, 55 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, IF, WB, FC
Frequently Asked Questions
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